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ent-Ezetimibe

CAS No. 1376614-99-1

ent-Ezetimibe ( ent-SCH 58235 )

Catalog No. M26200 CAS No. 1376614-99-1

Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ent-Ezetimibe
  • Note
    Research use only, not for human use.
  • Brief Description
    Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.?
  • Description
    Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor, and is a potent Nrf2 activator.ent-Ezetimibe (ent-SCH 58235) is the RRS-enantiomer of Ezetimibe. Ezetimibe is a potent cholesterol absorption inhibitor.?
  • Synonyms
    ent-SCH 58235
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    AChE; BChE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1376614-99-1
  • Formula Weight
    409.4
  • Molecular Formula
    C24H21F2NO3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@H](CC[C@H]1[C@@H](N(C1=O)c1ccc(F)cc1)c1ccc(O)cc1)c1ccc(F)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Deng QH, Wadepohl H, Gade LH. The synthesis of a new class of chiral pincer ligands and their applications in enantioselective catalytic fluorinations and the Nozaki-Hiyama-Kishi reaction. Chemistry. 2011 Dec 23;17(52):14922-8.
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