dBET6 ( dBET 6 )

Catalog No. M13051 CAS No. 1950634-92-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Group Booking Get Quotation Bulk Inquiry Add to Cart

Product Name

dBET6
Note

Research use only, not for human use.
Brief Description

dBET6 is a highly cell-permeable, optimized chemical degrader of BET bromodomain BED4, does not directly affect CDK9 localization.
Description

dBET6 is a highly cell-permeable, optimized chemical degrader of BET bromodomain BED4, does not directly affect CDK9 localization.
Synonyms

dBET 6
Pathway

PROTACs
Target

PROTAC
Recptor

BET
Research Area

——
Indication

——

CAS Number

1950634-92-0
Formula Weight

841.38
Molecular Formula

C42H45ClN8O7S
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM （ < 1 mg/ml refers to the product slightly soluble or insoluble )
SMILES

O=C(NCCCCCCCCNC(COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O)C[C@H]4C5=NN=C(C)N5C6=C(C(C)=C(C)S6)C(C7=CC=C(Cl)C=C7)=N4
Chemical Name

6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-[8-[[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]oxy]acetyl]amino]octyl]-2,3,9-trimethyl-, (6S)-

1. Winter GE, et al. Mol Cell. 2017 Jul 6;67(1):5-18.e19.
2. Cancer Discov. 2017 Aug;7(8):794.

Calculator

molnova catalog