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Home - Products - Chromatin/Epigenetic - COX - alpha-Spinasterol

alpha-Spinasterol

CAS No. 481-18-5

alpha-Spinasterol ( —— )

Catalog No. M24432 CAS No. 481-18-5

α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.?α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    alpha-Spinasterol
  • Note
    Research use only, not for human use.
  • Brief Description
    α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.?α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively.
  • Description
    α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.?α-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 μM and 7.76 μM, respectively.
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX-1;COX-2;TRPV1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    481-18-5
  • Formula Weight
    412.7
  • Molecular Formula
    C29H48O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: insoluble;H2O: insoluble
  • SMILES
    CC[C@@H](C(C)C)/C=C/[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Indiara, Brusco, Camila, et al. α-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.[J]. British Journal of Pharmacology, 2017.
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