Zuclopenthixol

CAS No. 53772-83-1

Zuclopenthixol ( alpha-Clopenthixol; Clopenthixol; Zuclopenthixol )

Catalog No. M18758 CAS No. 53772-83-1

Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 27 In Stock
50MG 35 In Stock
100MG 50 In Stock
200MG 72 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Zuclopenthixol
  • Note
    Research use only, not for human use.
  • Brief Description
    Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
  • Description
    Zuclopenthixol, also known as Cisordinol, Clopixol, Acuphase, zuclopentixol, is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1962 by Lundbeck. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol is not approved for use in the United States. Zuclopenthixol has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but no affinity for cholinergic muscarine receptors. It has weak histamine (H1) receptor affinity and no α2-adrenoceptor blocking activity.
  • Synonyms
    alpha-Clopenthixol; Clopenthixol; Zuclopenthixol
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    D1; D2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    53772-83-1
  • Formula Weight
    400.96
  • Molecular Formula
    C22H25ClN2OS
  • Purity
    98%
  • Solubility
    DMSO : ≥ 150 mg/mL; 374.10 mM
  • SMILES
    C1CN(CCN1CC/C=C\1/c2ccccc2Sc2c1cc(cc2)Cl)CCO
  • Chemical Name
    2-[4-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Khalifa AE: Zuclopenthixol facilitates memory retrieval in rats: possible involvement of noradrenergic and serotonergic mechanisms. Pharmacol Biochem Behav. 2003 Jul;75(4):755-62.
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