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Zuclopenthixol
CAS No. 53772-83-1
Zuclopenthixol ( alpha-Clopenthixol; Clopenthixol; Zuclopenthixol )
Catalog No. M18758 CAS No. 53772-83-1
Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 27 | In Stock |
|
| 50MG | 35 | In Stock |
|
| 100MG | 50 | In Stock |
|
| 200MG | 72 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameZuclopenthixol
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NoteResearch use only, not for human use.
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Brief DescriptionZuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
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DescriptionZuclopenthixol, also known as Cisordinol, Clopixol, Acuphase, zuclopentixol, is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1962 by Lundbeck. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol is not approved for use in the United States. Zuclopenthixol has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but no affinity for cholinergic muscarine receptors. It has weak histamine (H1) receptor affinity and no α2-adrenoceptor blocking activity.
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Synonymsalpha-Clopenthixol; Clopenthixol; Zuclopenthixol
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PathwayOthers
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TargetOther Targets
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RecptorD1; D2
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Research Area——
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Indication——
Chemical Information
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CAS Number53772-83-1
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Formula Weight400.96
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Molecular FormulaC22H25ClN2OS
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Purity98%
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SolubilityDMSO : ≥ 150 mg/mL; 374.10 mM
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SMILESC1CN(CCN1CC/C=C\1/c2ccccc2Sc2c1cc(cc2)Cl)CCO
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Chemical Name2-[4-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Khalifa AE: Zuclopenthixol facilitates memory retrieval in rats: possible involvement of noradrenergic and serotonergic mechanisms. Pharmacol Biochem Behav. 2003 Jul;75(4):755-62.
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