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Zelminemab

CAS No. 2225850-33-7

Zelminemab( —— )

Catalog No. M36779 CAS No. 2225850-33-7

Zelminemab (AMG-301) is a human monoclonal antibody designed to target and inhibit the PACAP type I (PAC1) receptor .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Zelminemab
  • Note
    Research use only, not for human use.
  • Brief Description
    Zelminemab (AMG-301) is a human monoclonal antibody designed to target and inhibit the PACAP type I (PAC1) receptor .
  • Description
    Zelminemab (AMG-301) is a human monoclonal antibody that inhibits PACAP type I (PAC1) receptor.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Sprague-Dawley rats, electricalstimulation was performed on the intact dura mater abovethe middle meningeal artery.Dosage:10 mg/kg Administration:i.v.; once Result:Induced an inhibition of stimulus-evoked nociceptive activity in the trigeminocervical com-plex (TCC).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2225850-33-7
  • Formula Weight
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Eloisa Rubio-Beltrán, et al. PACAP38 and PAC1 receptor blockade: a new target for headache? J Headache Pain. 2018 Aug 7;19(1):64. ?
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