ZPCK ( Z-L-Phe chloromethyl ketone;NSC 251810;SL 01 )

Catalog No. M13792 CAS No. 26049-94-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

ZPCK
Note

Research use only, not for human use.
Brief Description

ZPCK is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells.
Description

ZPCK (NSC 251810;SL 01) is a potent, pan autophagy inhibitor, inhibits the cargo degradation inside the vacuole and alters the process of autophagy in mammalian cells; also modulates autophagic flux in a novel model plant, Aponogeton madagascariensis.
Synonyms

Z-L-Phe chloromethyl ketone;NSC 251810;SL 01
Pathway

Autophagy
Target

Autophagy
Recptor

Autophagy
Research Area

——
Indication

——

CAS Number

26049-94-5
Formula Weight

331.80
Molecular Formula

C18H18ClNO3
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(OCC1=CC=CC=C1)N[C@H](C(CCl)=O)CC2=CC=CC=C2
Chemical Name

N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-carbamic acid, phenylmethyl ester

1. Mishra P, et al. Autophagy. 2017 Aug 9:1-17.

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