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ZK824190
CAS No. 2254001-81-3
ZK824190 ( —— )
Catalog No. M26523 CAS No. 2254001-81-3
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 512 | Get Quote |
|
| 10MG | 734 | Get Quote |
|
| 25MG | 1125 | Get Quote |
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| 50MG | 1512 | Get Quote |
|
| 100MG | 2043 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameZK824190
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NoteResearch use only, not for human use.
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Brief DescriptionZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA).
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DescriptionZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA). The IC50 values are 237, 1600 and 1850 nM for uPA, tPA, and Plasmin, respectively.(In Vivo):In rats with experimental autoimmune encephalomyelitis (EAE) model, ZK824190 (2?mg/kg; p.o.) exhibited a relatively high oral availability(F?=?55%; Cmax=?0.64?g/mL and AUC?=?2.2?h*g/mL) and a moderate half time of 2.8 h.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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Recptor5-HT3
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Research Area——
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Indication——
Chemical Information
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CAS Number2254001-81-3
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Formula Weight414.4
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Molecular FormulaC22H20F2N2O4
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Purity>98% (HPLC)
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Solubility——
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SMILESCC[C@@H](Oc1nc(Oc2cccc(c2)-c2cccc(CN)c2)c(F)cc1F)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kilpatrick GJ, et al. 1-(m-chlorophenyl)-biguanide, a potent high affinity 5-HT3 receptor agonist. Eur J Pharmacol. 1990 Jun 21;182(1):193-7.
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