Cart
sales@molnova.com
ZDLD20
CAS No. 2762279-02-5
ZDLD20( —— )
Catalog No. M35585 CAS No. 2762279-02-5
ZDLD20 is an orally active and selective CDK4 inhibitor, a β-carboline analog with anti-HCT116 and anticancer activity that inhibits colony formation, inhibits invasion and migration, induces apoptosis, and prevents the G1 phase of the cell cycle.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 73 | Get Quote |
|
| 5MG | 107 | Get Quote |
|
| 10MG | 176 | Get Quote |
|
| 25MG | 342 | Get Quote |
|
| 50MG | 548 | Get Quote |
|
| 100MG | 858 | Get Quote |
|
| 500MG | 1692 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameZDLD20
-
NoteResearch use only, not for human use.
-
Brief DescriptionZDLD20 is an orally active and selective CDK4 inhibitor, a β-carboline analog with anti-HCT116 and anticancer activity that inhibits colony formation, inhibits invasion and migration, induces apoptosis, and prevents the G1 phase of the cell cycle.
-
DescriptionZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51? μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2762279-02-5
-
Formula Weight386.45
-
Molecular FormulaC22H22N6O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(NC1=NC=C(C=C1)N2CCN(C)CC2)C3=NC=CC=4C=5C=CC=CC5NC34
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Deping Li, et al. Facile synthesis of C1-substituted β-carbolines as CDK4 inhibitors for the treatment of cancer. Bioorg Chem. 2022 Apr;121:105659.?
molnova catalog
related products
-
3-Deoxyaconitine
3-?Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization.
-
Procyanidin C1
Procyanidin C1 is a natural product with anti-inflammatory effects and induces apoptosis.
-
Phytohemagglutinin
Phytohemagglutinin is a lectin, isolated from the red kidney bean , induces apoptosis via increasing proapoptotic protein Bax and activating caspases-3.
