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Home - Products - Angiogenesis - EGFR - ZD-4190

ZD-4190

CAS No. 413599-62-9

ZD-4190 ( —— )

Catalog No. M20212 CAS No. 413599-62-9

ZD-4190 is a inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling used for the treatment of cancer.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 290 In Stock
10MG 435 In Stock
25MG 692 In Stock
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Biological Information

  • Product Name
    ZD-4190
  • Note
    Research use only not for human use.
  • Brief Description
    ZD-4190 is a inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling used for the treatment of cancer.
  • Description
    ZD-4190 is a inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling used for the treatment of cancer.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    EGFR
  • Recptor
    EGFR/VEGFR2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    413599-62-9
  • Formula Weight
    459.28
  • Molecular Formula
    C19H16BrFN6O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:20.83 mg/mL?(45.35 mM)
  • SMILES
    COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCn1ccnn1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yang M et al. PET imaging of early response to the tyrosine kinase inhibitor ZD4190. Eur J Nucl Med Mol Imaging. 2011 Jul;38(7):1237-47. doi: 10.1007/s00259-011-1742-z. Epub 2011 Mar 1.
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