ZD-0892

Research use only, not for human use.

ZD-0892 is a selective and potent inhibitor of neutrophil elastase, targeting human neutrophil elastase and porcine pancreatic elastase with Kis of 6.7 nM and 200 nM, respectively.

ZD-0892 is a selective and potent inhibitor of a neutrophil elastase with Kis of 6.7 and 200 nM for human neutrophil elastase and porcine pancreatic elastase, respectively.

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ZD0892 administration to DBA/2 mice infected with the EMC virus results in reduced myocardial elastolytic activity and coronary microvascular perfusion injury. ZD0892 decreases the pathologic severity of the myocardial lesions associated with murine viral myocarditis. ZD-0892 can reverse advanced pulmonary vascular disease produced in rats.

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Proteasome/Ubiquitin

Serine Protease

Serine Protease

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171964-73-1

499.52

C24H32F3N3O5

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (500.48 mM; Ultrasonic )

COc1ccc(cc1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F

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(-20℃)

With Ice Pack

≥ 2 years