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Home - Products - Proteasome/Ubiquitin - Serine Protease - APD597

APD597

CAS No. 897732-93-3

APD597( APD597 | APD-597 | APD 597 | JNJ-38431055 )

Catalog No. M17648 CAS No. 897732-93-3

APD597 is a GPR119 agonist, used in the treatment of type 2 diabetes.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    APD597
  • Note
    Research use only, not for human use.
  • Brief Description
    APD597 is a GPR119 agonist, used in the treatment of type 2 diabetes.
  • Description
    APD597, also known as JNJ-38431055, is a potent and selective GPR119 agonist, which is potential useful for the treatment of type 2 diabetes. GPR119 agonists mediate a unique nutrient-dependent dual elevation of both insulin and glucagon like peptide 1/glucose-dependent insulinotropic peptide levels in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    APD597 | APD-597 | APD 597 | JNJ-38431055
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Serine Protease
  • Recptor
    GPR119
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    897732-93-3
  • Formula Weight
    479.55
  • Molecular Formula
    C21H29N5O6S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 19 mg/mL; 39.62 mM
  • SMILES
    Cc1c(ccc(n1)S(=O)(=O)C)Nc1c(c(ncn1)OC1CCN(CC1)C(=O)OC(C)C)OC
  • Chemical Name
    isopropyl 4-((5-methoxy-6-((2-methyl-6-(methylsulfonyl)pyridin-3-yl)amino)pyrimidin-4-yl)oxy)piperidine-1-carboxylate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Buzard DJ, et al. Bioorg Med Chem Lett. 2014 Sep 1;24(17):4332-5.
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