ZBMA-1 ( —— )

Catalog No. M13088 CAS No. 1975145-64-2

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Datasheet

HNMR

HPLC

MSDS

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Product Name

ZBMA-1
Note

Research use only, not for human use.
Brief Description

ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex.
Description

ZBMA-1 is a potent HIV-1 replication inhibitor (IC50=1.01 uM) that efficiently protects APOBEC3G protein by targeting Vif-APOBEC3G complex; protected APOBEC3G from Vif-mediated degradation in a dose-dependent manner and induced nonfunctional proviruses, blocked Vif binding to Elongin C, does not affect the interactions between Vif and APOBEC3G or CBF-β.
Synonyms

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Pathway

Microbiology/Virology
Target

HIV
Recptor

HIV
Research Area

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Indication

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CAS Number

1975145-64-2
Formula Weight

325.17
Molecular Formula

C15H9BrN4
Purity

>98% (HPLC)
Solubility

——
SMILES

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Chemical Name

2-(1H-benzo[d]imidazol-2-yl)-3-(6-bromopyridin-3-yl)acrylonitrile

1. Zhang S, et al. Antiviral Res. 2015 Oct;122:20-7.

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