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Yohimbine
CAS No. 146-48-5
Yohimbine( —— )
Catalog No. M11995 CAS No. 146-48-5
Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameYohimbine
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NoteResearch use only, not for human use.
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Brief DescriptionYohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.
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DescriptionYohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C; shows moderate affinity for the α1 receptor, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, 5-HT2B, and D2 receptors, and weak affinity for the 5-HT1E, 5-HT2A, 5-HT5A, 5-HT7, and D3 receptors.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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RecptorAdrenergic Receptor
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number146-48-5
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Formula Weight354.4427
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Molecular FormulaC21H26N2O3
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCOC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)O
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Chemical NameYohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16α,17α)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Millan MJ, et al. Synapse. 2000 Feb;35(2):79-95.
2. Arthur JM, et al. Biochem Pharmacol. 1993 Jun 9;45(11):2337-41.
3. Pérez Pi?ero C, et al. Br J Pharmacol. 2012 May;166(2):721-36.
4. Baxter GS, et al. Br J Pharmacol. 1994 May;112(1):323-31.
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