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Home - Products - Angiogenesis - Adrenergic Receptor - Yohimbine

Yohimbine

CAS No. 146-48-5

Yohimbine ( —— )

Catalog No. M11995 CAS No. 146-48-5

Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Yohimbine
  • Note
    Research use only, not for human use.
  • Brief Description
    Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C.
  • Description
    Yohimbine is an indole alkaloid that has high affinity for the α2-adrenergic receptors with Ki of 1 nM for α2A, α2B and α2C; shows moderate affinity for the α1 receptor, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1F, 5-HT2B, and D2 receptors, and weak affinity for the 5-HT1E, 5-HT2A, 5-HT5A, 5-HT7, and D3 receptors.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    146-48-5
  • Formula Weight
    354.44
  • Molecular Formula
    C21H26N2O3
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    COC(=O)C1C(CCC2C1CC3C4=C(CCN3C2)C5=CC=CC=C5N4)O
  • Chemical Name
    Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16α,17α)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Millan MJ, et al. Synapse. 2000 Feb;35(2):79-95.
2. Arthur JM, et al. Biochem Pharmacol. 1993 Jun 9;45(11):2337-41.
3. Pérez Piero C, et al. Br J Pharmacol. 2012 May;166(2):721-36.
4. Baxter GS, et al. Br J Pharmacol. 1994 May;112(1):323-31.
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