Coelenterazine
CAS No. 55779-48-1
Coelenterazine ( Oplophorus, luciferin; Coelenterazine; CLZN )
Catalog No. M18810 CAS No. 55779-48-1
Coelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques.
Purity : 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
2MG | 133 | In Stock |
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5MG | 287 | In Stock |
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10MG | 502 | In Stock |
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25MG | 649 | In Stock |
|
100MG | Get Quote | In Stock |
|
200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameCoelenterazine
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NoteResearch use only, not for human use.
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Brief DescriptionCoelenterazine is a luminescent enzyme substrate, used for monitoring reporter genes in BRET, ELISA and HTS techniques.
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DescriptionCoelenterazine is the luciferin, the light-emitting molecule, found in many aquatic organisms across seven phyla. It is the substrate of many luciferases such as Renilla reniformis luciferase (Rluc), Gaussia luciferase (Gluc), and photoproteins, including aequorin, and obelin. Coelenterazine was used: (1) For Aequorin assays; (2) For measuring the intracellular calcium concentration in response to ionomycin or PMA using aequorin in COS-7 cells2; (3). In Bioluminescence imaging for analysing the presence of virus-dependent luciferase activity. Luminophore of the aequorin complex which is oxidized by oxygen to illuminate at 465 nm when Ca2+ binds to the complex; used to measure Ca2+ concentration in cells with high sensitivity and large dynamic range.
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SynonymsOplophorus, luciferin; Coelenterazine; CLZN
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number55779-48-1
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Formula Weight423.47
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Molecular FormulaC26H21N3O3
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Purity98%
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Solubility——
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SMILESOc1ccc(Cc2nc3c(Cc4ccccc4)[nH]c(cn3c2=O)c2ccc(O)cc2)cc1
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Chemical Name8-benzyl-2-(4-hydroxybenzyl)-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Morse D, Tannous B A. A water-soluble coelenterazine for sensitive in vivo imaging of coelenterate luciferases.[J]. Molecular Therapy the Journal of the American Society of Gene Therapy, 2012, 20(4):692-3.
molnova catalog
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