Cart
sales@molnova.com
YYA-021
CAS No. 144217-65-2
YYA-021 ( YYA 021;YYA021 )
Catalog No. M11874 CAS No. 144217-65-2
A small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 33 | In Stock |
|
| 5MG | 53 | In Stock |
|
| 10MG | 65 | In Stock |
|
| 25MG | 140 | In Stock |
|
| 50MG | 194 | In Stock |
|
| 100MG | 250 | In Stock |
|
| 500MG | 614 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameYYA-021
-
NoteResearch use only, not for human use.
-
Brief DescriptionA small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
-
DescriptionA small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity; shows wide tissue distribution and relatively high distribution volumes, and has promise for intravenous administration.
-
SynonymsYYA 021;YYA021
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorGp120
-
Research AreaInfection
-
Indication——
Chemical Information
-
CAS Number144217-65-2
-
Formula Weight317.43
-
Molecular FormulaC18H27N3O2
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(NC1CC(C)(C)NC(C)(C)C1)C(NC2=CC=C(C)C=C2)=O
-
Chemical NameEthanediamide, N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Hashimoto C, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7884-9.
2. Otsuki H, et al. J Gen Virol. 2013 Dec;94(Pt 12):2710-6.
3. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.
2. Otsuki H, et al. J Gen Virol. 2013 Dec;94(Pt 12):2710-6.
3. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.
molnova catalog
related products
-
DAPTA
DAPTA is a synthetic peptide, functions as a viral entry inhibitor by targeting selectively CCR5, and shows potent anti-HIV activities. DAPTA potently inhibits specific CD4-dependent binding of gp120 Bal (IC50 = 0.06 nM) and CM235 (IC50 = 0.32 nM) to CCR5.
-
PD 404182
PD 404182 (PD404182, PD-404182) is a heterocyclic iminobenzothiazine derivative with antimicrobial and anti-inflammatory properties, a potent inhibitor of human DDAH1 activity (IC50=9 uM) and elevates cellular ADMA levels.
-
Zidovudine
A nucleoside reverse transcriptase inhibitor (NRTI) that used to prevent and treat HIV/AIDS.
