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YYA-021

CAS No. 144217-65-2

YYA-021( YYA 021 | YYA021 )

Catalog No. M11874 CAS No. 144217-65-2

A small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 33 In Stock
5MG 53 In Stock
10MG 65 In Stock
25MG 140 In Stock
50MG 194 In Stock
100MG 250 In Stock
500MG 614 In Stock
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Biological Information

  • Product Name
    YYA-021
  • Note
    Research use only, not for human use.
  • Brief Description
    A small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity.
  • Description
    A small-molecule CD4 mimic that acts as a highly potent HIV entry inhibitor with IC50 of 9 uM against YTA48P virus with no significant cytotoxicity; shows wide tissue distribution and relatively high distribution volumes, and has promise for intravenous administration.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    YYA 021 | YYA021
  • Pathway
    Microbiology/Virology
  • Target
    HIV
  • Recptor
    Gp120
  • Research Area
    Infection
  • Indication
    ——

Chemical Information

  • CAS Number
    144217-65-2
  • Formula Weight
    317.4259
  • Molecular Formula
    C18H27N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=C(NC1CC(C)(C)NC(C)(C)C1)C(NC2=CC=C(C)C=C2)=O
  • Chemical Name
    Ethanediamide, N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hashimoto C, et al. Bioorg Med Chem. 2013 Dec 15;21(24):7884-9. 2. Otsuki H, et al. J Gen Virol. 2013 Dec;94(Pt 12):2710-6. 3. Narumi T, et al. Bioorg Med Chem. 2013 May 1;21(9):2518-26.
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