Xenalipin( BW 207U )

Catalog No. M27180 CAS No. 84392-17-6

Xenalipin has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Xenalipin
Note

Research use only, not for human use.
Brief Description

Xenalipin has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.
Description

Xenalipin has hypolipidemic. It reduces blood cholesterol and triglycerides in rats.
In Vitro

——
In Vivo

4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys. Animal Model:Diet-induced hypercholesterolemic African green monkeys Dosage:15-60 mg/kg Administration:Oral administration (p.o.)Result:Reduced serum LDL-cholesterol concentrations.
Synonyms

BW 207U
Pathway

Others
Target

Other Targets
Recptor

SIRT1| SIRT2| SIRT3
Research Area

——
Indication

——

Chemical Information

CAS Number

84392-17-6
Formula Weight

266.219
Molecular Formula

C14H9F3O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 250 mg/mL (939.07 mM)
SMILES

OC(=O)c1ccccc1-c1ccc(cc1)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Disch JS, et al. Discovery of thieno[3,2-d]pyrimidine-6-carboxamides as potent inhibitors of SIRT1, SIRT2, and SIRT3. J Med Chem. 2013 May 9;56(9):3666-79.

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