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Xanomeline tartrate

CAS No. 152854-19-8

Xanomeline tartrate( —— )

Catalog No. M35083 CAS No. 152854-19-8

Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 44 In Stock
10MG 61 In Stock
25MG 90 In Stock
50MG 136 In Stock
100MG 195 In Stock
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Biological Information

  • Product Name
    Xanomeline tartrate
  • Note
    Research use only, not for human use.
  • Brief Description
    Xanomeline tartrate (LY 246708 tartrate) is an M1 and M4 mAChR agonist with antipsychotic-like activity that improves cognition and can be used in studies of schizophrenia and Alzheimer's disease.
  • Description
    Xanomeline (LY 246708) is the potent agonist of muscarinic M1/M4 receptor with antipsychotic-like activity. Xanomeline (LY 246708) increases neuronal excitability.Xanomeline (LY 246708) can be used for the research of schizophrenia.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Cebus apella monkeys Dosage:0.5-3 mg/kg Administration:s.c.; 1-3 hours Result:Induced salivation and vomiting in some monkeys.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    152854-19-8
  • Formula Weight
    431.5
  • Molecular Formula
    C18H29N3O7S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (579.37 mM; Ultrasonic )
  • SMILES
    O[C@@H]([C@H](O)C(O)=O)C(O)=O.CCCCCCOc1nsnc1C1=CCCN(C)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kreir M, et al. Role of Kv7.2/Kv7.3 and M1 muscarinic receptors in the regulation of neuronal excitability in hiPSC-derived neurons. Eur J Pharmacol. 2019;858:172474. ?
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