Cart
sales@molnova.com
Home - Products - Others - Other Targets - NCT-503

NCT-503

CAS No. 1916571-90-8

NCT-503( NCT-503 | NCT 503 | NCT503 )

Catalog No. M18172 CAS No. 1916571-90-8

NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 60 In Stock
2MG 33 In Stock
5MG 54 In Stock
10MG 87 In Stock
25MG 187 In Stock
50MG 332 In Stock
100MG 492 In Stock
200MG 690 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    NCT-503
  • Note
    Research use only, not for human use.
  • Brief Description
    NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells.
  • Description
    NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 2.5 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NCT-503 | NCT 503 | NCT503
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PHGDH(Cell-free)| FLT3| AXL
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1916571-90-8
  • Formula Weight
    408.49
  • Molecular Formula
    C20H23F3N4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL 122.41 mM;
  • SMILES
    Cc1cc(nc(c1)NC(=S)N1CCN(CC1)Cc1ccc(cc1)C(F)(F)F)C
  • Chemical Name
    N-(4,6-dimethylpyridin-2-yl)-4-(4-(trifluoromethyl)benzyl)piperazine-1-carbothioamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Pacold ME, et al. A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate. Nat Chem Biol. 2016 Jun;12(6):452-8.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • NADPH tetrasodium sa...

    NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate (NADP+) and acts as an electron donor in various biological reactions.

  • Tilorone dihydrochlo...

    Tilorone dihydrochloride is the first recognized synthetic, small molecular weight compound that is an orally active interferon inducer, used as an antiviral drug.

  • AU-224

    AU-224 is an orally available benzamide derivative that is a potent gastrointestinal prokinetic.

Sign In Join Free