XY101

Research use only, not for human use.

XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).

XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).(In Vitro):XY101 effectively inhibits cell growth, colony formation and expression of androgen receptor (AR), AR-V7 and prostate specific antigen (PSA).(In Vivo):XY101 exhibits significant antitumor activities during the treatment period with tumor growth inhibition and is well tolerated without obvious body weight loss.

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Others

Other Targets

α-synuclein

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2349368-16-5

563.5

C25H20F7NO4S

>98% (HPLC)

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CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)-c2ccc(cc2F)C(O)(C(F)(F)F)C(F)(F)F)cc1

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(-20℃)

With Ice Pack

≥ 2 years