XY101 ( —— )

Catalog No. M26510 CAS No. 2349368-16-5

XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	260	Get Quote
10MG	447	Get Quote
25MG	714	Get Quote
50MG	1017	Get Quote
100MG	1368	Get Quote
500MG	2673	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

XY101
Note

Research use only, not for human use.
Brief Description

XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).
Description

XY101 is a selective, metabolically stable and orally available agonist of RORγ inverse(IC50 of 30 nM and a Kd of 380 nM).(In Vitro):XY101 effectively inhibits cell growth, colony formation and expression of androgen receptor (AR), AR-V7 and prostate specific antigen (PSA).(In Vivo):XY101 exhibits significant antitumor activities during the treatment period with tumor growth inhibition and is well tolerated without obvious body weight loss.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

α-synuclein
Research Area

——
Indication

——

Chemical Information

CAS Number

2349368-16-5
Formula Weight

563.5
Molecular Formula

C25H20F7NO4S
Purity

>98% (HPLC)
Solubility

——
SMILES

CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(cc2)-c2ccc(cc2F)C(O)(C(F)(F)F)C(F)(F)F)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Pujols J, et al. Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):10481-10486.

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