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XY028-133

CAS No. 2229974-73-4

XY028-133( —— )

Catalog No. M33174 CAS No. 2229974-73-4

XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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5MG	282	Get Quote
10MG	496	Get Quote
25MG	814	Get Quote
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100MG	2376	Get Quote
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Biological Information

Product Name

XY028-133
Note

Research use only, not for human use.
Brief Description

XY028-133 is a PROTAC-based CDK4/6 degrader for the study of tumors.
Description

XY028-133 (example 14) is a PROTAC-based CDK4/6 degrader with anti-tumor activity, which consists of ligands for von Hippel-Lindau and CDK.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PROTACs | CDK
Research Area

——
Indication

——

Chemical Information

CAS Number

2229974-73-4
Formula Weight

1002.23
Molecular Formula

C53H67N11O7S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (49.89 mM; Ultrasonic )
SMILES

CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(CC3)C(=O)CCCCCC(=O)N[C@H](C(=O)N3C[C@H](O)C[C@H]3C(=O)NCc3ccc(cc3)-c3scnc3C)C(C)(C)C)nc2n(C2CCCC2)c1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. JIN, Jian， et al. COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER. Patent. US2017/065027.

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