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WZ4002
CAS No. 1213269-23-8
WZ4002 ( WZ4002; WZ-4002; WZ 4002 )
Catalog No. M10796 CAS No. 1213269-23-8
WZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50 of 2 nM/8 nM.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 41 | In Stock |
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| 10MG | 60 | In Stock |
|
| 25MG | 107 | In Stock |
|
| 50MG | 177 | In Stock |
|
| 100MG | 312 | In Stock |
|
| 200MG | 464 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameWZ4002
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NoteResearch use only, not for human use.
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Brief DescriptionWZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50 of 2 nM/8 nM.
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DescriptionWZ4002 is a novel, mutant-selective EGFR inhibitor for EGFR(L858R)/(T790M) with IC50 of 2 nM/8 nM; does not inhibit ERBB2 phosphorylation (T798I).
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SynonymsWZ4002; WZ-4002; WZ 4002
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR (L858R); EGFR (L858R/T790M)
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1213269-23-8
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Formula Weight494.18
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Molecular FormulaC25H27ClN6O3
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Purity>98%(HPLC)
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SolubilityDMSO:13 mg/mL (26.3 mM);Ethanol:<1 mg/mL (<1 mM);Water：<1 mg/mL (<1 mM)
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SMILESC=CC(NC1=CC=CC(OC2=NC(NC3=CC=C(N4CCN(C)CC4)C=C3OC)=NC=C2Cl)=C1)=O
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Chemical NameN-(3-((5-chloro-2-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)oxy)phenyl)acrylamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Zhou W, et al. Nature. 2009, 462(7276), 1070-1074.
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