Vamorolone

Research use only, not for human use.

Vamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer.

Vamorolone is an orally active dissociative steroidal anti-inflammatory drug and membrane-stabilizer. Vamorolone improves muscular dystrophy without side effects. Vamorolone displays effective NF-κB inhibition and substantially decreases hormonal effects.

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Animal Model:C57BL/6 mice (experimental autoimmune encephalomyelitis)Dosage:30 mg/kg Administration:Orally; daily for 20 days (starting one day prior to MOG 33-55 peptide immunization and continuing)Result:Reduced CNS inflammation in murine experimental autoimmune encephalomyelitis.

VBP15

Apoptosis

NF-κB

Glucocorticoid Receptor|Mineralocorticoid Receptor|NF-κB

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13209-41-1

356.46

C22H28O4

>98% (HPLC)

DMSO:62.5 mg/mL (175.34 mM; Need ultrasonic)

C[C@H](C[C@@H]([C@@H]1CC2)[C@]3(C)CC=C1[C@@](C)(C=C1)C2=CC1=O)[C@@]3(C(CO)=O)O

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(-20℃)

With Ice Pack

≥ 2 years