Valspodar ( PSC-833;SDZ PSC-833 )

Catalog No. M10809 CAS No. 121584-18-7

A highly potent multidrug-resistance modifier that acts as a P-glycoprotein inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Valspodar
Note

Research use only, not for human use.
Brief Description

A highly potent multidrug-resistance modifier that acts as a P-glycoprotein inhibitor.
Description

A highly potent multidrug-resistance modifier that acts as a P-glycoprotein inhibitor; exhibits effectivity at preventing cancer cell resistance to chemotherapeutics.Blood Cancer Phase 2 Discontinued
Synonyms

PSC-833;SDZ PSC-833
Pathway

Membrane Transporter/Ion Channel
Target

P-glycoprotein
Recptor

P-glycoprotein
Research Area

Cancer
Indication

Blood cancer

Chemical Information

CAS Number

121584-18-7
Formula Weight

1214.62
Molecular Formula

C63H111N11O12
Purity

>98% (HPLC)
Solubility

DMSO: 12 mg/mL
SMILES

O=C([C@H](C(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@H](CC(C)C)N(C)C([C@H](C(C)C)NC([C@H](CC(C)C)N(C)C(CN(C)C([C@H](C(C)C)N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)N(C)[C@@H](C([C@H](C)C/C=C/C)=O)C1=O
Chemical Name

Cyclosporin A, 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Boesch D, et al. Cancer Res. 1991 Aug 15;51(16):4226-33.
2. Ehrlich PH, et al. Anticancer Res. 1997 Jan-Feb;17(1A):129-33.
3. Hu XF, et al. Clin Cancer Res. 1996 Apr;2(4):713-20.

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