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Home - Products - Membrane Transporter/Ion Channel - P-glycoprotein - Valspodar

Valspodar

CAS No. 121584-18-7

Valspodar ( PSC-833;SDZ PSC-833 )

Catalog No. M10809 CAS No. 121584-18-7

A highly potent multidrug-resistance modifier that acts as a P-glycoprotein inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Valspodar
  • Note
    Research use only, not for human use.
  • Brief Description
    A highly potent multidrug-resistance modifier that acts as a P-glycoprotein inhibitor.
  • Description
    A highly potent multidrug-resistance modifier that acts as a P-glycoprotein inhibitor; exhibits effectivity at preventing cancer cell resistance to chemotherapeutics.Blood Cancer Phase 2 Discontinued
  • Synonyms
    PSC-833;SDZ PSC-833
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    P-glycoprotein
  • Recptor
    P-glycoprotein
  • Research Area
    Cancer
  • Indication
    Blood cancer

Chemical Information

  • CAS Number
    121584-18-7
  • Formula Weight
    1214.62
  • Molecular Formula
    C63H111N11O12
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 12 mg/mL
  • SMILES
    O=C([C@H](C(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@H](CC(C)C)N(C)C([C@@H](C)NC([C@H](C)NC([C@H](CC(C)C)N(C)C([C@H](C(C)C)NC([C@H](CC(C)C)N(C)C(CN(C)C([C@H](C(C)C)N1)=O)=O)=O)=O)=O)=O)=O)=O)=O)N(C)[C@@H](C([C@H](C)C/C=C/C)=O)C1=O
  • Chemical Name
    Cyclosporin A, 6-[(2S,4R,6E)-4-methyl-2-(methylamino)-3-oxo-6-octenoic acid]-7-L-valine-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Boesch D, et al. Cancer Res. 1991 Aug 15;51(16):4226-33.
2. Ehrlich PH, et al. Anticancer Res. 1997 Jan-Feb;17(1A):129-33.
3. Hu XF, et al. Clin Cancer Res. 1996 Apr;2(4):713-20.
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