Valbenazine

CAS No. 1025504-45-3

Valbenazine( NBI-98854 )

Catalog No. M10117 CAS No. 1025504-45-3

A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 60 In Stock
5MG 122 In Stock
10MG 177 In Stock
25MG 402 In Stock
50MG 582 In Stock
100MG 831 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Valbenazine
  • Note
    Research use only, not for human use.
  • Brief Description
    A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.
  • Description
    A novel, highly selective vesicular monoamine transporter 2 (VMAT2) inhibitor; is approved for the treatment of tardive dyskinesia.Other Indication Phase 3 Clinical(In Vitro):Valbenazine exhibits VMAT2 binding affinity in rat striatum and human platelets with Kis of 110 and 150 nM, respectively. (In Vivo):Valbenazine (10 mg/kg; orally) induces ptosis (primarily an adrenergic response) and increases plasma prolactin primarily a dopaminergic response.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NBI-98854
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Other Targets
  • Research Area
    Other Indications
  • Indication
    Other Disease

Chemical Information

  • CAS Number
    1025504-45-3
  • Formula Weight
    418.5695
  • Molecular Formula
    C24H38N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    CC(C)CC1CN2CCC3=CC(=C(C=C3C2CC1OC(=O)C(C(C)C)N)OC)OC
  • Chemical Name
    L-Valine, (2R,3R,11bR)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-yl ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. O'Brien CF, et al. Mov Disord. 2015 Oct;30(12):1681-7.
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