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Vagistat
CAS No. 65899-73-2
Vagistat( (±)-Tioconazole )
Catalog No. M15506 CAS No. 65899-73-2
Tioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 41 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVagistat
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NoteResearch use only, not for human use.
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Brief DescriptionTioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast.
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DescriptionTioconazole is an antifungal medication of the Imidazole class used to treat infections caused by a fungus or yeast. Tioconazole topical (skin) preparations are also available for ringworm, jock itch, athlete's foot, and tinea versicolor or "sun fungus". Tioconazole interacts with 14-alpha demethylase, a cytochrome P-450 enzyme that converts lanosterol to ergosterol, an essential component of the yeast membrane. In this way, tioconazole inhibits ergosterol synthesis, resulting in increased cellular permeability.
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In Vitro——
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In Vivo——
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Synonyms(±)-Tioconazole
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PathwayMicrobiology/Virology
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TargetAntifection
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Recptor14-α Demethylase
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number65899-73-2
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Formula Weight387.71
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Molecular FormulaC16H13Cl3N2OS
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Purity>98% (HPLC)
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SolubilityEthanol: 78 mg/mL (201.18 mM); DMSO: 78 mg/mL (201.18 mM)
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SMILESC1=CC(=C(C=C1Cl)Cl)C(CN2C=CN=C2)OCC3=C(SC=C3)Cl
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Chemical Name1-(2-((2-chlorothiophen-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Enmein
Enmein shows a significant inhibitory effect toward human tumor cell K562 with IC(50) values ranging from 3.2 μg/ml to 8.2 μg/ml.
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Prunin
Prunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp.
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Altenuene
Altenuene is a mycotoxin, it frequently occurs in food and feed items infested by fungi of the genus Alternaria. Altenuene demonstrates moderate activity against Staphylococcus aureus. Altenuene also exhibits cytotoxic activity against lung cancer cell line A549, breast cancer cell line MDA-MB-231 and pancreatic cancer cell line PANC-1.
