Cart
sales@molnova.com
VTP50469
CAS No. 2169916-18-9
VTP50469 ( —— )
Catalog No. M23981 CAS No. 2169916-18-9
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 337 | In Stock |
|
| 10MG | 537 | In Stock |
|
| 25MG | 868 | In Stock |
|
| 50MG | 1161 | In Stock |
|
| 100MG | 1584 | In Stock |
|
| 200MG | 2133 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVTP50469
-
NoteResearch use only, not for human use.
-
Brief DescriptionVTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
-
DescriptionVTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis;Menin-MLL interaction
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2169916-18-9
-
Formula Weight630.8
-
Molecular FormulaC32H47FN6O4S
-
Purity>98% (HPLC)
-
SolubilityDMSO:125 mg/mL (198.15 mM; Need ultrasonic)
-
SMILESCC(C)N(C(C)C)C(=O)C1=C(C=CC(=C1)F)OC2=CN=CN=C2N3CC4(C3)CCN(CC4)CC5CCC(CC5)NS(=O)(=O)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Krivtsov AV, et al. A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia. Cancer Cell. 2019 Dec 9;36(6):660-673.e11.
molnova catalog
related products
-
Flurochloridone
Flurochloridone is a selective herbicide. Flurochloridone induces apoptosis and is regulated by mitochondrial dysfunction and oxidative stresses.
-
Millepachine
Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.
-
TD52
TD52 is an orally active inhibitor of cancerous inhibitor of PP2A (CIP2A). TD52 is an Erlotinib derivative and indirectly reduced CIP2A by disturbing Elk1 binding to the CIP2A promoter.
