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VPC-13163

CAS No. 6637-10-1

VPC-13163 ( VPC 13163; VPC13163; NSC 52361; NSC52361; NSC52361; 2,3-dihydro-2,3'-Bi-1H-indole )

Catalog No. M27934 CAS No. 6637-10-1

VPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    VPC-13163
  • Note
    Research use only, not for human use.
  • Brief Description
    VPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line.
  • Description
    VPC-13163 has strong anti-proliferative activity against LNCaP and Enzalutamide-resistant prostate cancer cell lines (MR49F) whereas it did not affect the growth of AR independent PC3 cell line. It also inhibits Prostate Specific Antigen (PSA) in both LNCaP and MR49F and reduces expression of AR target genes, PSA and TMPRSS2. These findings suggest that VPC-13566 exhibits AR BF3 specific mechanism of action.
  • Synonyms
    VPC 13163; VPC13163; NSC 52361; NSC52361; NSC52361; 2,3-dihydro-2,3'-Bi-1H-indole
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    CCK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6637-10-1
  • Formula Weight
    234.3
  • Molecular Formula
    C16H14N2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C1C(Nc2ccccc12)c1c[nH]c2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Eric Lattmann, et al. A preparation of novel ureido - and amido-?pyrazolone derivatives, useful as CCK receptor ligands and CCK antagonists. WO2004106306A1
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