Cart
sales@molnova.com
Home - Products - Microbiology/Virology - Filovirus - VGTI-A3-03

VGTI-A3-03

CAS No. ——

VGTI-A3-03( —— )

Catalog No. M17091 CAS No. ——

VGTI-A3-03 is a novel potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    VGTI-A3-03
  • Note
    Research use only, not for human use.
  • Brief Description
    VGTI-A3-03 is a novel potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM).
  • Description
    VGTI-A3-03 is a novel potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM), directly bind DENV capsid protein; also demonstrates some inhibitory activity against DENV1, DENV4, and WNV; does not inhibit viral RNA replication or secretion of viral particles, significantly diminishe secreted particles in treated cells, the binding pocket in the capsid molecule is at the dimerization interface; VGTI-A3-03 is incorporated into virus particles released from infected cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Filovirus
  • Recptor
    Filovirus
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    483.608
  • Molecular Formula
    C26H21N5OS2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3-amino-6-phenyl-N-(4-phenylthiazol-2-yl)-5,6,7,8-tetrahydrothieno[2,3-b][1,6]naphthyridine-2-carboxamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Smith JL, et al. Antiviral Res. 2018 Apr 27;155:12-19.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • FGI-104

    FGI-104 is a small-molecule inhibitor of filovirus that exhibits potent antiviral activity against of EBOV (EC90=330 nM, ZEBOV) and MARV (EC50=2.5 uM, MARV-Ci67).

  • VGTI-A3-03

    VGTI-A3-03 is a novel potent, highly virus-specific inhibitor of DENV replication with greatest activity against DENV serotype 2 (IC50=25 nM).

  • IHVR-19029

    IHVR-19029 is a novel antiviral compound that acts as ER α-glucosidase inhibitor.

Sign In Join Free