VAS2870

CAS No. 722456-31-7

VAS2870( VAS 2870 )

Catalog No. M17580 CAS No. 722456-31-7

VAS2870 is a NADPH oxidase (NOX) inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 47 In Stock
10MG 88 In Stock
25MG 170 In Stock
50MG 311 In Stock
100MG 464 In Stock
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Biological Information

  • Product Name
    VAS2870
  • Note
    Research use only, not for human use.
  • Brief Description
    VAS2870 is a NADPH oxidase (NOX) inhibitor.
  • Description
    VAS 2870 is a NADPH oxidase (Nox) inhibitor that enhances TGF-β-induced apoptosis of liver tumor cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    VAS 2870
  • Pathway
    PI3K/Akt/mTOR signaling
  • Target
    GSK-3
  • Recptor
    NADPH oxidase (NOX)
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    722456-31-7
  • Formula Weight
    360.4
  • Molecular Formula
    C18H12N6OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 83.3 mg/mL. 231.14 mM;
  • SMILES
    C12=C(SC3=NC4=C(C=CC=C4)O3)N=CN=C1N(CC5=CC=CC=C5)N=N2
  • Chemical Name
    7-(2-Benzoxazolylthio)-3-(phenylmethyl)-3H-1,2,3-triazolo[4,5-d]pyrimidine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.ten Freyhaus H, et al. Novel Nox inhibitor VAS2870 attenuates PDGF-dependent smooth muscle cell chemotaxis, but not proliferation. Cardiovasc Res. 2006 Jul 15;71(2):331-41.
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