Cart
sales@molnova.com
VAL-083
CAS No. 23261-20-3
VAL-083 ( Dianhydrogalactitol; Dianhydrodulcitol )
Catalog No. M24063 CAS No. 23261-20-3
VAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 107 | In Stock |
|
| 5MG | 164 | In Stock |
|
| 10MG | 222 | In Stock |
|
| 25MG | 374 | In Stock |
|
| 50MG | 555 | In Stock |
|
| 100MG | 790 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVAL-083
-
NoteResearch use only, not for human use.
-
Brief DescriptionVAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
-
DescriptionVAL-083 is an alkylating compound that creates N7 methylation on DNA. It also has antitumor activity.
-
SynonymsDianhydrogalactitol; Dianhydrodulcitol
-
PathwayCell Cycle/DNA Damage
-
TargetDNA/RNA Synthesis
-
RecptorDNA Alkylator
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number23261-20-3
-
Formula Weight146.1
-
Molecular FormulaC6H10O4
-
Purity>98% (HPLC)
-
SolubilityDMF :90 mg/mL (615.85 mM);H2O:40 mg/mL (273.71 mM; Need ultrasonic)
-
SMILESO[C@H]([C@H](O)[C@@]1([H])OC1)[C@@]2([H])CO2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kaiji Hu, et al. Abstract 811: VAL083, a novel N7 alkylating agent, surpasses NSC 362856 activity and inhibits cancer stem cells providing a new potential treatment option for glioblastoma multiforme. Cancer Research. 2012 Mar 31-Apr 4.
molnova catalog
related products
-
6-Mercaptopurine mon...
ercaptopurine is a widely used antileukemic agent and immunosuppressive drug that inhibits de novo purine synthesis through incorporation of thiopurine methyltransferase metabolites into DNA and RNA.
-
Clofarabine
Clofarabine(Clolar; Clofarex) inhibits the enzymatic activities of ribonucleotide reductase (IC50 = 65 nM) and DNA polymerase.
-
Gentisin
Gentisin is a novel inhibitor of vascular smooth muscle cells (VSMC) proliferation with an IC50 value of 7.84 μM. Gentisin has mutagenic activity.
