RU320521

CAS No. 2262452-06-0

RU320521 ( RU.521 )

Catalog No. M20220 CAS No. 2262452-06-0

RU.521 (RU320521) is a potent?dsDNA?inhibitor (IC50 : 700?nM) inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 52 In Stock
5MG 87 In Stock
10MG 155 In Stock
25MG 253 In Stock
50MG 356 In Stock
100MG 530 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    RU320521
  • Note
    Research use only not for human use.
  • Brief Description
    RU.521 (RU320521) is a potent?dsDNA?inhibitor (IC50 : 700?nM) inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
  • Description
    RU.521 (RU320521) is a potent?dsDNA?inhibitor (IC50 : 700?nM) inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS.
  • Synonyms
    RU.521
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    dsDNA/cGAS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2262452-06-0
  • Formula Weight
    414.22
  • Molecular Formula
    C19H11Cl2N4O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL?(301.04 mM)
  • SMILES
    Cc1nn(-c2nc3c(Cl)c(Cl)ccc3[nH]2)c(O)c1C1OC(=O)c2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Vincent J et al. Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun. 2017 Sep 29;8(1):750.
molnova catalog
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