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Upacicalcet

CAS No. 1333218-50-0

Upacicalcet( —— )

Catalog No. M34460 CAS No. 1333218-50-0

Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 167 Get Quote
5MG 257 Get Quote
10MG 380 Get Quote
25MG 615 Get Quote
50MG 873 Get Quote
100MG 1161 Get Quote
500MG 2322 Get Quote
1G Get Quote Get Quote
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Biological Information

  • Product Name
    Upacicalcet
  • Note
    Research use only, not for human use.
  • Brief Description
    Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.
  • Description
    Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1333218-50-0
  • Formula Weight
    351.76
  • Molecular Formula
    C11H14ClN3O6S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C(NC[C@@H](C(O)=O)N)=O)C1=CC(S(=O)(=O)O)=CC(Cl)=C1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596. ?
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