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Upacicalcet

CAS No. 1333218-50-0

Upacicalcet( —— )

Catalog No. M34460 CAS No. 1333218-50-0

Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.

Purity : >98% (HPLC)

COA

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HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
2MG	167	Get Quote
5MG	257	Get Quote
10MG	380	Get Quote
25MG	615	Get Quote
50MG	873	Get Quote
100MG	1161	Get Quote
500MG	2322	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

Upacicalcet
Note

Research use only, not for human use.
Brief Description

Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.
Description

Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).
In Vitro

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In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

1333218-50-0
Formula Weight

351.76
Molecular Formula

C11H14ClN3O6S
Purity

>98% (HPLC)
Solubility

——
SMILES

N(C(NC[C@@H](C(O)=O)N)=O)C1=CC(S(=O)(=O)O)=CC(Cl)=C1C
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596. ?

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