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USP8-IN-22d

CAS No. 924296-18-4

USP8-IN-22d ( —— )

Catalog No. M16622 CAS No. 924296-18-4

A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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25MG	566	Get Quote
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Biological Information

Product Name

USP8-IN-22d
Note

Research use only, not for human use.
Brief Description

A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM.
Description

A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM; shows no inhibitory activity for USP7 (IC50>100 uM).
Synonyms

——
Pathway

Proteasome/Ubiquitin
Target

DUB
Recptor

DUB
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

924296-18-4
Formula Weight

337.33
Molecular Formula

C20H11N5O
Purity

>98% (HPLC)
Solubility

DMSO: 20 mg/mL
SMILES

C1=CC=C(C=C1)CON=C2C3=CC=CC=C3C4=NC(=C(N=C42)C#N)C#N
Chemical Name

9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(phenylmethoxy)imino]-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Colombo M, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.

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