USP8-IN-22d

CAS No. 924296-18-4

USP8-IN-22d ( —— )

Catalog No. M16622 CAS No. 924296-18-4

A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    USP8-IN-22d
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM.
  • Description
    A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM; shows no inhibitory activity for USP7 (IC50>100 uM).
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    DUB
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    924296-18-4
  • Formula Weight
    337.33
  • Molecular Formula
    C20H11N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 20 mg/mL
  • SMILES
    C1=CC=C(C=C1)CON=C2C3=CC=CC=C3C4=NC(=C(N=C42)C#N)C#N
  • Chemical Name
    9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(phenylmethoxy)imino]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Colombo M, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.
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