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URB602

CAS No. 565460-15-3

URB602 ( URB602, URB-602, URB 602 )

Catalog No. M18820 CAS No. 565460-15-3

URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 58 In Stock
50MG 102 In Stock
100MG 178 In Stock
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Biological Information

  • Product Name
    URB602
  • Note
    Research use only, not for human use.
  • Brief Description
    URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.
  • Description
    URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 μM for the rat brain enzyme. Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.
  • Synonyms
    URB602, URB-602, URB 602
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    rat brain MGL
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    565460-15-3
  • Formula Weight
    295.38
  • Molecular Formula
    C19H21NO2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 31 mg/mL; 104.95 mM
  • SMILES
    C1CCC(CC1)OC(=O)Nc1cccc(c1)c1ccccc1
  • Chemical Name
    cyclohexyl [1,1'-biphenyl]-3-ylcarbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hohmann AG, et al. An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 Jun 23;435(7045):1108-12.
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