URB602

CAS No. 565460-15-3

URB602 ( URB602, URB-602, URB 602 )

Catalog No. M18820 CAS No. 565460-15-3

URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
10MG 35 In Stock
25MG 58 In Stock
50MG 102 In Stock
100MG 178 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    URB602
  • Note
    Research use only, not for human use.
  • Brief Description
    URB602 is a specific monoacylglycerol lipase (MGL) inhibitor, which inhibits rat brain MGL (IC50: 28±4 μM) through a noncompetitive mechanism.
  • Description
    URB602 is a selective inhibitor of monoglycerol lipase (MGL), exhibiting an IC50 of 28 μM for the rat brain enzyme. Pretreatment with the monoacylglycerol lipase inhibitor URB602 protects from the long-term consequences of neonatal hypoxic-ischemic brain injury in rats. URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices.
  • Synonyms
    URB602, URB-602, URB 602
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    rat brain MGL
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    565460-15-3
  • Formula Weight
    295.38
  • Molecular Formula
    C19H21NO2
  • Purity
    98%
  • Solubility
    DMSO : ≥ 31 mg/mL; 104.95 mM
  • SMILES
    C1CCC(CC1)OC(=O)Nc1cccc(c1)c1ccccc1
  • Chemical Name
    cyclohexyl [1,1'-biphenyl]-3-ylcarbamate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hohmann AG, et al. An endocannabinoid mechanism for stress-induced analgesia. Nature. 2005 Jun 23;435(7045):1108-12.
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