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UNC669

CAS No. 1314241-44-5

UNC669( —— )

Catalog No. M17941 CAS No. 1314241-44-5

UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 43 In Stock
25MG 71 In Stock
50MG 100 In Stock
100MG 178 In Stock
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Biological Information

  • Product Name
    UNC669
  • Note
    Research use only, not for human use.
  • Brief Description
    UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
  • Description
    UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
  • In Vitro
    L3MBTL1, a paralogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a methylation state-dependent manner and contributes to higher order chromatin structure and transcriptional repression. Similar to L3MBTL1, the closely related protein, L3MBTL3, also contains three MBT repeats and has been shown to play a role in meduloblastoma formation and normal hematopoiesis in humans.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    L3MBTL1| L3MBTL3| L3MBTL4
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    1314241-44-5
  • Formula Weight
    338.24
  • Molecular Formula
    C15H20BrN3O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 50 mg/mL 147.82 mM;
  • SMILES
    c1c(cncc1Br)C(=O)N1CCC(CC1)N1CCCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Herold JM, et al. J Med Chem. 2011, 54(7), 2504-2511.
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