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UNC669

CAS No. 1314241-44-5

UNC669( —— )

Catalog No. M17941 CAS No. 1314241-44-5

UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
10MG	43	In Stock
25MG	71	In Stock
50MG	100	In Stock
100MG	178	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

UNC669
Note

Research use only, not for human use.
Brief Description

UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
Description

UNC669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.
In Vitro

L3MBTL1, a paralogue of Drosophila tumor suppressor lethal(3)malignant brain tumor (l(3)mbt), binds histones in a methylation state-dependent manner and contributes to higher order chromatin structure and transcriptional repression. Similar to L3MBTL1, the closely related protein, L3MBTL3, also contains three MBT repeats and has been shown to play a role in meduloblastoma formation and normal hematopoiesis in humans.
In Vivo

——
Synonyms

——
Pathway

Autophagy
Target

Autophagy
Recptor

L3MBTL1| L3MBTL3| L3MBTL4
Research Area

Others-Field
Indication

——

Chemical Information

CAS Number

1314241-44-5
Formula Weight

338.24
Molecular Formula

C15H20BrN3O
Purity

>98% (HPLC)
Solubility

DMSO : 50 mg/mL 147.82 mM;
SMILES

c1c(cncc1Br)C(=O)N1CCC(CC1)N1CCCC1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Herold JM, et al. J Med Chem. 2011, 54(7), 2504-2511.

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