Cart
sales@molnova.com
UNC0224
CAS No. 1197196-48-7
UNC0224( UNC 0224 | UNC-0224 )
Catalog No. M10700 CAS No. 1197196-48-7
A potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 60 | In Stock |
|
| 5MG | 88 | In Stock |
|
| 10MG | 146 | In Stock |
|
| 25MG | 336 | In Stock |
|
| 50MG | 529 | In Stock |
|
| 100MG | 754 | In Stock |
|
| 500MG | 1548 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameUNC0224
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays.
-
DescriptionA potent, selective G9a/GLP inhibitor with IC50 of 57 nM and 58 nM CLOT biochemical assays; dispalys >1000-fold selectivity for G9a over SET7/9, SET8, PRMT3 and JMJD2E (IC50>4 uM).
-
In Vitro——
-
In Vivo——
-
SynonymsUNC 0224 | UNC-0224
-
PathwayChromatin/Epigenetic
-
TargetHMTase
-
RecptorHMTase
-
Research AreaOther Indications
-
Indication——
Chemical Information
-
CAS Number1197196-48-7
-
Formula Weight485.6653
-
Molecular FormulaC26H43N7O2
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCN1CCC(NC2=C3C=C(OC)C(OCCCN(C)C)=CC3=NC(N4CCN(C)CCC4)=N2)CC1
-
Chemical Name4-Quinazolinamine, 7-[3-(dimethylamino)propoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Liu F, et al. J Med Chem. 2010 Aug 12;53(15):5844-57.
2. Liu F, et al. J Med Chem. 2009 Dec 24;52(24):7950-3.
molnova catalog
related products
-
NV01
NV01 is a small-molecule antagonist of the H3K9me3 binding to UHRF1 tandem tudor domain (TTD) with Kd of 5 uM.
-
AMI-1
A specific inhibitor of PRMTs (protein arginine methyltransferases), but not lysine methyltransferases.
-
WDR5 WIN site inhibi...
WDR5 WIN site inhibitor C3 is a potent, specific WIN (WDR5 interaction) site inhibitor of WDR5 with Kd of 1.3 nM.
