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UNC-2170

CAS No. 1648707-58-7

UNC-2170( UNC2170 )

Catalog No. M12518 CAS No. 1648707-58-7

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
2MG	61	Get Quote
5MG	102	Get Quote
10MG	170	Get Quote
25MG	372	Get Quote
50MG	556	Get Quote
100MG	791	Get Quote
500MG	1611	Get Quote
1G	Get Quote	Get Quote

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Biological Information

Product Name

UNC-2170
Note

Research use only, not for human use.
Brief Description

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
Description

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain; is highly cell permeant with no significant measureable cellular efflux; shows modestly potent, demonstrates at least 17-fold selectivity for 53BP1 as compared to nine other Kme reader proteins.
In Vitro

——
In Vivo

——
Synonyms

UNC2170
Pathway

Apoptosis
Target

MDM2-p53
Recptor

MDM2-p53
Research Area

——
Indication

——

Chemical Information

CAS Number

1648707-58-7
Formula Weight

313.23
Molecular Formula

C14H21BrN2O
Purity

>98% (HPLC)
Solubility

In Vitro:?Methanol : 125 mg/mL (399.07 )
SMILES

CC(C)(C)NCCCNC(=O)C1=CC(=CC=C1)Br.C(=CC(=O)O)C(=O)O
Chemical Name

3-bromo-N-(3-(tert-butylamino)propyl)benzamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81.

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