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UM-171
CAS No. 1448724-09-1
UM-171 ( UM171 )
Catalog No. M11925 CAS No. 1448724-09-1
UM-171 is a potent agonist of human hematopoietic stem cell self-renewal.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameUM-171
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NoteResearch use only, not for human use.
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Brief DescriptionUM-171 is a potent agonist of human hematopoietic stem cell self-renewal.
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DescriptionUM-171 is a potent agonist of human hematopoietic stem cell self-renewal, shows 10 to 20 times more potent than UM729 with effective concentrations of 17 to 19 nM; enables a robust ex vivo expansion of human CB cells with functionally validated long-term in vivo repopulating capability.Blood Cancer Phase 2 Clinical
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SynonymsUM171
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaCancer
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IndicationBlood cancer
Chemical Information
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CAS Number1448724-09-1
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Formula Weight487.94
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Molecular FormulaC25H27N9
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Purity>98% (HPLC)
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Solubility——
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SMILESN[C@H]1CC[C@H](NC2=C3C(NC4=C3C=CC(C5=NN(C)N=N5)=C4)=NC(CC6=CC=CC=C6)=N2)CC1
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Chemical Name(1r,4r)-N1-(2-benzyl-7-(2-methyl-2H-tetrazol-5-yl)-9H-pyrimido[4,5-b]indol-4-yl)cyclohexane-1,4-diamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Fares I, et al. Science. 2014 Sep 19;345(6203):1509-12.
2. Li X, et al. Stem Cell Res. 2017 May;21:32-39.
3. Zonari E, et al. Stem Cell Reports. 2017 Apr 11;8(4):977-990.
2. Li X, et al. Stem Cell Res. 2017 May;21:32-39.
3. Zonari E, et al. Stem Cell Reports. 2017 Apr 11;8(4):977-990.
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