Cart
sales@molnova.com
Home - Products - Angiogenesis - PDE - UK-369003

UK-369003

CAS No. 334827-98-4

UK-369003 ( Gisadenafil besylate )

Catalog No. M14135 CAS No. 334827-98-4

UK-369003 (Gisadenafil besylate) is a novel, potent, selective, orally bioavailable PDE5 inhibitor with IC50 of 1.23 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 224 Get Quote
50MG 799 Get Quote
100MG 1206 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    UK-369003
  • Note
    Research use only, not for human use.
  • Brief Description
    UK-369003 (Gisadenafil besylate) is a novel, potent, selective, orally bioavailable PDE5 inhibitor with IC50 of 1.23 nM.
  • Description
    UK-369003 (Gisadenafil besylate) is a novel, potent, selective, orally bioavailable PDE5 inhibitor with IC50 of 1.23 nM, displays 117-fold selectivity over PDE6; demonstrates efficacy in patients with lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH).COPD Phase 2 Discontinued
  • Synonyms
    Gisadenafil besylate
  • Pathway
    Angiogenesis
  • Target
    PDE
  • Recptor
    PDE
  • Research Area
    Inflammation/Immunology
  • Indication
    COPD

Chemical Information

  • CAS Number
    334827-98-4
  • Formula Weight
    677.79
  • Molecular Formula
    C23H33N7O5S.C6H6O3S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CCC1=C2C(=NN1CCOC)C(=O)NC(=N2)C3=C(N=CC(=C3)S(=O)(=O)N4CCN(CC4)CC)OCC.C1=CC=C(C=C1)S(=O)(=O)O
  • Chemical Name
    5-[2-Ethoxy-5-[(4-ethyl-1-piperazinyl)sulfonyl]-3-pyridinyl]-3-ethyl-2,6-dihydro-2-(2-methoxyethyl)-7H-pyrazolo[4,3-d]pyrimidin-7-one benzenesulfonate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rawson DJ, et al. Bioorg Med Chem. 2012 Jan 1;20(1):498-509.
2. Martínez-Salamanca JI, et al. Eur Urol. 2011 Sep;60(3):527-35.
3. Watson KJ, et al. Drug Metab Dispos. 2011 Jul;39(7):1203-13.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Heptaminol hydrochlo...

    Heptaminol hydrochloride is a vasoconstrictor, used in the treatment of low blood pressure, particularly orthostatic hypotension.

  • Robustine

    Robustine is a natural product, exhibits inhibitory potency against human phosphodiesterase 5 (hPDE5A) in vitro.

  • PDE9-IN-(S)-C33

    PDE9-IN-(S)-C33 is a potent and selective inhibitor of PDE9 (IC50 = 11 nM). PDE9-IN-(S)-C33 can be used for central nervous system diseases and diabetes research.

Sign In Join Free