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UAMC3203

CAS No. 2271358-64-4

UAMC3203( UAMC 3203 | UAMC-3203 )

Catalog No. M20094 CAS No. 2271358-64-4

UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    UAMC3203
  • Note
    Research use only, not for human use.
  • Brief Description
    UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
  • Description
    UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
  • In Vitro
    ——
  • In Vivo
    No toxicity is observed in mice after repeated injections of UAMC-3203 (20 μmol/kg; injected intraperitoneally; daily, over a period of 4 weeks). Animal Model:Wild type mice derived from a Gpx4 fl/fl breeding Dosage:20 μmol/kg Administration:Injected intraperitoneally; daily, over a period of 4 weeks Result:No toxicity was observed.
  • Synonyms
    UAMC 3203 | UAMC-3203
  • Pathway
    Apoptosis
  • Target
    Ferroptosis
  • Recptor
    Ferroptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2271358-64-4
  • Formula Weight
    471.66
  • Molecular Formula
    C25H37N5O2S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:199.3 mM
  • SMILES
    O=S(=O)(NCCN1CCNCC1)c1ccc(NC2CCCCC2)c(NCc2ccccc2)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Devisscher L et al. Discovery of Novel Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.
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