Trilostane ( Desopan; Modrefen; Vetoryl; WIN 24,540 )

Catalog No. M11506 CAS No. 13647-35-3

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HNMR

HPLC

MSDS

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Product Name

Trilostane
Note

Research use only, not for human use.
Brief Description

Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
Description

Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
Synonyms

Desopan; Modrefen; Vetoryl; WIN 24,540
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

3 β-hydroxysteroid dehydrogenase
Research Area

Endocrinology
Indication

——

CAS Number

13647-35-3
Formula Weight

329.43
Molecular Formula

C20H27NO3
Purity

>98%(HPLC)
Solubility

DMSO: 65 mg/mL (197.31 mM)
SMILES

N#CC1=C(O)[C@@]2([H])O[C@@]23[C@]([C@@]4([H])CC[C@@]5(C)[C@](CC[C@@H]5O)([H])[C@]4([H])CC3)(C)C1
Chemical Name

(1aR,4aR,4bS,6aS,7S,9aS,9bS,11aS)-2,7-dihydroxy-4a,6a-dimethyl-1a,4,4a,4b,5,6,6a,7,8,9,9a,9b,10,11-tetradecahydrocyclopenta[7,8]phenanthro[1,10a-b]oxirene-3-carbonitrile.

1.Puddefoot JR, et al. Expert Opin PharmacOthers. 2006 Dec;7(17):2413-9.

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