Tilianin

CAS No. 4291-60-5

Tilianin( —— )

Catalog No. M21503 CAS No. 4291-60-5

Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 149 Get Quote
10MG 221 Get Quote
25MG 372 Get Quote
50MG 552 Get Quote
100MG 786 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Tilianin
  • Note
    Research use only, not for human use.
  • Brief Description
    Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.
  • Description
    Tilianin is a flavonoid glycoside of Dragocephalum moldavicum L.
  • In Vitro
    Tilianin (10 μM, 20 μM) reduced secretion of LPS (1 μg/mL)-induced proinflammatory cytokine in RAW264.7 macrophage cell.
  • In Vivo
    Tilianin (10 mg/kg; i.p.) is a potential agent for ameliorating LPS-induced acute lung injury (ALI).Tilianin shows Tmax=10.8 min,Cmax=176.9 nmol/L, AUC0-∞= 17.4 min*μmol/L in mice. Animal Model:C57BL/6 mouse Dosage:10 mg/kg Administration:Intraperitoneal injection Result:Attenuated infiltration of macrophages and histopathological changes and improved inflammation.Animal Model:Male FVB mice (6-10 weeks) Dosage:10 mg/kg (Pharmacokinetic Analysis)Administration:Oral gavage Result:Tmax(10.8 min), Cmax(176.9 nmol/L), AUC0-∞(17.4 min*μmol/L).
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4291-60-5
  • Formula Weight
    446.4
  • Molecular Formula
    C22H22O10
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (112.01 mM)
  • SMILES
    COc(cc1)ccc1C(Oc1c2c(O)cc(O[C@@H]([C@@H]([C@H]3O)O)O[C@H](CO)[C@H]3O)c1)=CC2=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sergienko TO et al. Moldavoside--new flavonoid glycoside of Dragocephalum moldavicum L. Farm Zh. 1968;23(2):75-8.
molnova catalog
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