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TiY
CAS No. ——
TiY( TIC Fluorescent Probe TiY )
Catalog No. M16973 CAS No. ——
TiY (TIC Fluorescent Probe TiY) is the first TIC (tumor initiating cell)-specific fluorescent chemical probe, target vimentin, a marker for epithelial-to-mesenchymal transition (EMT).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameTiY
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NoteResearch use only, not for human use.
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Brief DescriptionTiY (TIC Fluorescent Probe TiY) is the first TIC (tumor initiating cell)-specific fluorescent chemical probe, target vimentin, a marker for epithelial-to-mesenchymal transition (EMT).
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DescriptionTiY (TIC Fluorescent Probe TiY) is the first TIC (tumor initiating cell)-specific fluorescent chemical probe, target vimentin, a marker for epithelial-to-mesenchymal transition (EMT); selectively stains TICs over differentiated tumor cells or normal cells, and facilitates the visualization and enrichment of functionally active TICs from patient tumors; also shows anti-TIC activity with low toxicity to non-TICs at high concentration.
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In Vitro——
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In Vivo——
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SynonymsTIC Fluorescent Probe TiY
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PathwayOthers
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TargetFluorescent Dye
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RecptorFluorescent Dye
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight541.875
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Molecular FormulaC29H35BClF2N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name(E)-N-(2-(3-(3-(tert-butyl)-2-propoxystyryl)-5,5-difluoro-1-methyl-5H-5l4,6l4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-10-yl)ethyl)-2-chloroacetamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lee YA, et al. Angew Chem Int Ed Engl. 2018 Jan 26.
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TiY
TiY (TIC Fluorescent Probe TiY) is the first TIC (tumor initiating cell)-specific fluorescent chemical probe, target vimentin, a marker for epithelial-to-mesenchymal transition (EMT).
