
Thiostrepton
CAS No. 1393-48-2
Thiostrepton( Bryamycin | NSC 81722 | NSC 170365 | Thiactin | Thiostreptin A )
Catalog No. M11641 CAS No. 1393-48-2
Thiostrepton is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
25MG | 27 | In Stock |
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50MG | 35 | In Stock |
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100MG | 50 | In Stock |
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200MG | Get Quote | In Stock |
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500MG | Get Quote | In Stock |
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1G | Get Quote | In Stock |
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Biological Information
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Product NameThiostrepton
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NoteResearch use only, not for human use.
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Brief DescriptionThiostrepton is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria.
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DescriptionThiostrepton is a one of the CYCLIC PEPTIDES from Streptomyces that is active against gram-positive bacteria. In veterinary medicine, it has been used in mastitis caused by gram-negative organisms and in dermatologic disorders. (In Vitro):Thiostrepton (0.01-1000 μM; 48 hours) suppresses cell viability in A2780 and HEC-1A.(In Vivo):Thiostrepton (i.p.; 17 mg/kg) reduces the tumorigenicity of Ewing's sarcoma (EWS) cells. Tumor volumes in control mice have increased ~6-fold from the initiation of treatment, while their Thiostrepton-treated counterparts increase only ~1.7-fold, exhibiting a ~3.5-fold reduction, relative to controls.
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In Vitro——
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In VivoAnimal Model:Athymic (BALB/c nu/nu) nude mice bearing A4573 cells Dosage:17 mg/kg Administration:Administered i.p.Result:Treatment inhibited the growth of EWS-derived tumors in vivo.
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SynonymsBryamycin | NSC 81722 | NSC 170365 | Thiactin | Thiostreptin A
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorDNA synthesis
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Research AreaInfection
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Indication——
Chemical Information
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CAS Number1393-48-2
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Formula Weight1664.89
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Molecular FormulaC72H85N19O18S5
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Purity>98% (HPLC)
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SolubilityDMSO: 40mg/mL
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SMILESNC[S=N]H(C)C(O)=O
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Chemical NameThiostrepton
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kuiper EG, Conn GL. J Biol Chem. 2014 Sep 19;289(38):26189-200.
molnova catalog



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