Cart
sales@molnova.com
Home - Products - Others - Other Targets - Thioacetazone

Thioacetazone

CAS No. 104-06-3

Thioacetazone( Diazam | Neotibil | Neustab )

Catalog No. M21119 CAS No. 104-06-3

Thioacetazone is a thiosemicarbazone that?thioacetazone treatment of pulmonary tuberculosis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 43 Get Quote
5MG 72 Get Quote
10MG 87 Get Quote
25MG 158 Get Quote
50MG 236 Get Quote
100MG 350 Get Quote
200MG 516 Get Quote
500MG 795 Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Thioacetazone
  • Note
    Research use only, not for human use.
  • Brief Description
    Thioacetazone is a thiosemicarbazone that?thioacetazone treatment of pulmonary tuberculosis.
  • Description
    Thioacetazone is a thiosemicarbazone that?thioacetazone treatment of pulmonary tuberculosis.(In Vitro):Thiacetazone is a prodrug that is activated by the mycobacterial monooxygenase EthA, which is also the activator of two other anti-tuberculosis agents, Ethionamide and Isoxyl.(In Vivo):aminobenzaldehydethiosemicarbazone formed/min/mg cytosolic protein, respectively. The ability to metabolize Thiacetazone is the same in the livers of cat, mouse and human, but lagged significantly in that of rat.
  • In Vitro
    Thiacetazone is a prodrug that is activated by the mycobacterial monooxygenase EthA, which is also the activator of two other anti-tuberculosis agents, Ethionamide and Isoxyl.
  • In Vivo
    The Km and Vmax values for the N-deacetylation of Thiacetazone are 0.57 mM and 0.123 nmol of p-aminobenzaldehydethiosemicarbazone formed/min/mg cytosolic protein, respectively. The ability to metabolize Thiacetazone is the same in the livers of cat, mouse and human, but lagged significantly in that of rat.
  • Synonyms
    Diazam | Neotibil | Neustab
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    others
  • Research Area
    Infection
  • Indication
    Mycobacterium Avium-intracellulare Infection

Chemical Information

  • CAS Number
    104-06-3
  • Formula Weight
    236.29
  • Molecular Formula
    C10H12N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (423.21 mM)
  • SMILES
    CC(=O)Nc1ccc(/C=N/NC(N)=S)cc1
  • Chemical Name
    Acetamide N-(4-(((aminothioxomethyl)hydrazono)methyl)phenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.K.A.-T.A.a.G.T.S.: Hong. A controlled comparison of thiacetazone (thioacetazone) plus isoniazid with pas plus isoniazid in Hong Kong[J]. tubercle 1968 49(3):243-280.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Oleclumab

    Oleclumab (MEDI9447) is a human anti-CD73 monoclonal antibody with anticancer activity that inhibits the extracellular enzyme CD73 nucleic acid exonuclease activity, inhibits the adenosine pathway, and can be used for the study of metastatic desmoplasia-resistant prostate cancer.

  • (+)-Bicuculline meth...

    (+)-Bicuculline methiodide is a γ-aminobutyric acid type A (GABAA) receptor blocker that crosses the rat blood-brain barrier (BBB) and blocks epileptogens, which can be used to study neurological disorders such as epilepsy. (+)-Bicuculline methiodide reduces liver injury in septic rats.

  • 16a17a-Epoxy-4-Pregn...

    16a17a-Epoxy-4-Pregnen-320-Dione is a chemical compound.

Sign In Join Free