MID-1
CAS No. 312608-54-1
MID-1 ( —— )
Catalog No. M22748 CAS No. 312608-54-1
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 147 | In Stock |
|
10MG | 222 | In Stock |
|
25MG | 410 | In Stock |
|
50MG | 605 | In Stock |
|
100MG | 860 | In Stock |
|
500MG | 1728 | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMID-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionMID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
-
DescriptionMID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorMG53-IRS-1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number312608-54-1
-
Formula Weight293.3
-
Molecular FormulaC12H11N3O4S
-
Purity>98% (HPLC)
-
SolubilityDMSO:31.25 mg/mL?(106.55 mM;?Need ultrasonic)
-
SMILESCCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.
molnova catalog
related products
-
Thymine
Thymine is found in the nucleic acid DNA. In RNA thymine is replaced with uracil in most cases. In DNA, thymine binds to adenine via two hydrogen bonds to assist in stabilizing the nucleic acid structures.
-
Prosaikogenin D
Prosaikogenin D is a natural product extracted from the roots of Buleurum bicaule Helm (Apiaceae) with anti-cancer activity.
-
Indicine hydrochlori...
The herbs of Heliotropium indicum.