MID-1
CAS No. 312608-54-1
MID-1 ( —— )
Catalog No. M22748 CAS No. 312608-54-1
MID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 147 | In Stock |
|
10MG | 222 | In Stock |
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25MG | 410 | In Stock |
|
50MG | 605 | In Stock |
|
100MG | 860 | In Stock |
|
500MG | 1728 | In Stock |
|
1G | Get Quote | In Stock |
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Biological Information
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Product NameMID-1
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NoteResearch use only, not for human use.
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Brief DescriptionMID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
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DescriptionMID-1 is an inhibitor of MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) interaction.?It disrupts molecular association of MG53 with IRS-1 and abolishes MG53-induced IRS-1 ubiquitination and degradation in skeletal muscle, leading to elevated IRS-1 expression level and increased insulin signaling and glucose uptake.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMG53-IRS-1
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Research Area——
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Indication——
Chemical Information
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CAS Number312608-54-1
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Formula Weight293.3
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Molecular FormulaC12H11N3O4S
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Purity>98% (HPLC)
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SolubilityDMSO:31.25 mg/mL?(106.55 mM;?Need ultrasonic)
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SMILESCCOc1ccc(cc1)C(=O)Nc1ncc(s1)[N+]([O-])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Lee H, et, al. MG53-IRS-1 (Mitsugumin 53-Insulin Receptor Substrate-1) Interaction Disruptor Sensitizes Insulin Signaling in Skeletal Muscle. J Biol Chem. 2016 Dec 23;291(52):26627-26635.
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