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Tenilsetam

CAS No. 86696-86-8

Tenilsetam ( Piperazinone,3-(2-thienyl)- (9CI) )

Catalog No. M22229 CAS No. 86696-86-8

Tenilsetam is an endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer's disease (AD) treatment.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tenilsetam
  • Note
    Research use only, not for human use.
  • Brief Description
    Tenilsetam is an endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer's disease (AD) treatment.
  • Description
    Tenilsetam is an endonuclease modulator; a nootropic agent and advanced glycation end product (AGE) inhibitor having potential for Alzheimer's disease (AD) treatment.In vitro, tenilsetam inhibited endothelial proliferation at lower doses, while inducing apoptosis at high doses.?Leucocyte adhesion was only inhibited at high doses.?Sprouting angiogenesis of bovine retinal endothelial cells was promoted at lower doses (
  • Synonyms
    Piperazinone,3-(2-thienyl)- (9CI)
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    AGE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    86696-86-8
  • Formula Weight
    182.24
  • Molecular Formula
    C8H10N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1NCCN[C@]1([H])c2ccc[s]2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jennifer Hoffmann , Alex Alt, Jihong Lin, Günther Lochnit,et al. Tenilsetam prevents early diabetic retinopathy without correcting pericyte loss.Thromb Haemost. 2006 Apr;95(4):689-95.
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