Temanogrel

CAS No. 887936-68-7

Temanogrel ( APD791 )

Catalog No. M24910 CAS No. 887936-68-7

Temanogrel is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 237 In Stock
10MG 354 In Stock
25MG 592 In Stock
50MG 843 In Stock
100MG 1143 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Temanogrel
  • Note
    Research use only, not for human use.
  • Brief Description
    Temanogrel is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).
  • Description
    Temanogrel is a highly selective antagonist of the 5-HT2A receptor (Ki: 4.9 nM).
  • Synonyms
    APD791
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    5-HT2A
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    887936-68-7
  • Formula Weight
    436.5
  • Molecular Formula
    C24H28N4O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (286.37 mM; Need ultrasonic)
  • SMILES
    Cn1nccc1-c(cc(cc1)NC(c2cc(OC)ccc2)=O)c1OCCN1CCOCC1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xiong Y, et al. Discovery and structure-activity relationship of 3-methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): a highly selective 5-hydroxytryptamine2A receptor inverse agonist for the treatment of arterial thrombosis. J Med Chem. 2010 Jun 10;53(11):4412-21.
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