
TRAM-34
CAS No. 289905-88-0
TRAM-34( TRAM-34 | TRAM34 | TRAM 34 )
Catalog No. M18371 CAS No. 289905-88-0
TRAM-34(Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450.
Purity : >98% (HPLC)






Size | Price / USD | Stock | Quantity |
10MG | 39 | In Stock |
![]() ![]() |
25MG | 73 | In Stock |
![]() ![]() |
50MG | 133 | In Stock |
![]() ![]() |
100MG | 176 | In Stock |
![]() ![]() |
200MG | 228 | In Stock |
![]() ![]() |
500MG | 383 | In Stock |
![]() ![]() |
1G | Get Quote | In Stock |
![]() ![]() |
Biological Information
-
Product NameTRAM-34
-
NoteResearch use only, not for human use.
-
Brief DescriptionTRAM-34(Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450.
-
DescriptionTRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli, and does not block cytochrome P450.
-
In Vitro——
-
In Vivo——
-
SynonymsTRAM-34 | TRAM34 | TRAM 34
-
PathwayOthers
-
TargetOther Targets
-
RecptorIKCa1 (KCa3.1)
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number289905-88-0
-
Formula Weight344.84
-
Molecular FormulaC22H17ClN2
-
Purity>98% (HPLC)
-
SolubilityDMSO : ≥ 3.5 mg/mL; 10.15 mM
-
SMILESn1(nccc1)C(c1ccccc1)(c1ccccc1)c1c(cccc1)Cl
-
Chemical Name1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference



-
Elamipretide
Elamipretide (SS-31, MTP-131, Bendavia) is a novel cell-permeable antioxidant tetrapeptide (D-Arg-dimethylTyr-Lys-Phe-NH2) that targets inner mitochondrial membrane and prevents oxidative damage of neuronal cells and other cell types.
-
S- (+)-Rolipram
S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.
-
Divalproex Sodium
Divalproex Sodium binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings.