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TP-10

CAS No. 898563-00-3

TP-10 ( —— )

Catalog No. M26489 CAS No. 898563-00-3

TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

TP-10
Note

Research use only, not for human use.
Brief Description

TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.
Description

TP-10 is a selective inhibitor of PDE10A against other PDEs with IC50 of 0.8 nM.(In Vivo):TP-10 is active in the mouse behavioral model for positive symptoms. TP-10 demonstrates good in vitro and in vivo activity with extremely high intrinsic clearance (CLint) of t>1000 mL/min/kg in mouse liver microsomes (MLM) in assay.
Synonyms

——
Pathway

Angiogenesis
Target

PDE
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

898563-00-3
Formula Weight

460.5
Molecular Formula

C26H19F3N4O
Purity

>98% (HPLC)
Solubility

——
SMILES

FC(F)(F)Cn1cc(c(n1)-c1ccc(OCc2ccc3ccccc3n2)cc1)-c1ccncc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Tadros W, Boulos AL. Selective hydrogenation of ergosterol and its acetate. Helv Chim Acta. 1975 Apr 23;58(3):668-71.

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